Kisspeptin

WHAT IS KISSPEPTIN?

Kisspeptin is produced from the hypothalamus and is responsible for a cascade of cell to cell communication, resulting in production of the hormones, luteinizing, and follicle-stimulating hormones created from the pituitary gland, which are then released into the blood. These hormones stimulate testes and ovaries to produce the sex steroids testosterone and oestradiol, responsible for the physical and emotional changes associated with puberty.

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WHAT ARE THE ORIGINS OF KISSPEPTIN?

Kisspeptins are a group of proteins essential for fertility. The first gene member was discovered in 1996 by researchers in Hershey, Pennsylvania where it received its name after the city’s chocolate ‘Kisses’.

HOW IS KISSPEPTIN CONTROLLED?

Kisspeptin is normally released in tandem with two other hormones, neurokinin B and dynorphin. The nerve cells producing kisspeptin, dynorphin and neurokinin B, are referred to as KNDy (‘candy’). It is still unclear exactly what the roles of neurokinin B and dynorphin are, however they appear to influence the release of Kisspeptin.

HOW DOES KISSPEPTIN WORK?

Men undergoing unbalanced TRT programs may experience unhealthy drops in both LH (luteinizing hormone) and FSH (follicle-stimulating hormone) levels. The exogenous testosterone administered as a consequence acts to slow their release.

These potential disruptions in LH and FSH levels normally demonstrate the necessity of regularly monitoring all hormone levels throughout therapy. (Not just testosterone levels).

Following Kisspeptin administration, men will usually experience significant increases in circulating levels of both luteinizing hormone (LH) and follicle-stimulating hormone (FSH) due to its clinical function as an “upstream stimulator of gonadotrophin releasing hormone (GnRH) neurons.”

BENEFITS OF KISSPEPTIN FOR MEN

Kisspeptin enters into receptor sites in the pituitary gland, starting a reaction that causes the gland to release neurotransmitters. Those neurotransmitters then signal the release of LH and FH. These hormones have a role to play in the production of testosterone and oestradiol. Without Kisspeptin, this entire chain reaction would be compromised.

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towards achieving your health goals.

Step One

Consultation-Discovery

MEDICAL HISTORY

We’ll check your medical history, discuss diet, lifestyle and health goals. This gives Peak Male Institute a better understanding of your needs. This information, along with comprehensive lab work and medical exam provides a good baseline to design your individually tailored program.

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Step Two

Physical Exam

PHYSICAL EXAM

The physical exam is a precursor to your lab analysis and blood test results. Your medical exam and blood panel will give our HRT/TRT Doctors the personalized data we need to prescribe your custom-tailored Peptide therapy plan.

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Step Three

Lab Analysis-Diagnostics

LAB ANALYSIS

We will order comprehensive lab work, which may include measuring testosterone, growth hormone, dihydrotestosterone, thyroid, c-reactive protein, dehydroepiandrosterone, fsh, lh, psa, homocysteine, b12, vitamin d, magnesium, and other health biomarkers to define your individual biochemistry.

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PERSONALIZED TREATMENT

A comprehensive plan is designed to meet your unique biological needs. Our experts will closely monitor your health, hormone levels, progress, and make any necessary adjustments. Our follow up and support system is designed to provide you with the personalized attention you need during your treatment program.
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YOU MUST BE 25 YEARS OR OLDER TO QUALIFY – Age will be verified via proper credentials. DO NOT APPLY for the program if you are under 25 years of age.

  1. Once we have your Medical History Form, we will schedule a time for your initial consultation/exam with a Physician to review your medical history either In Person or via a Telehealth Exam.
  2. After initial review and consultation a physician will then discuss your best treatment options and recommended Lab Work to get you started.
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